Author Affiliations: Cerebrovascular Division, Johns Hopkins University School of Medicine, Baltimore, Md.
Grand Rounds at The Johns Hopkins Hospital Section
Editors: David B. Hellmann, MD, D. William Schlott, MD, Stephen D.
Sisson, MD, The Johns Hopkins Hospital, Baltimore, Md; David S. Cooper, MD,
Contributing Editor, JAMA.
This article presents the case of a healthy 46-year-old man who experienced
a dissection of the internal carotid artery. The diagnosis of this condition
is not usually clear-cut, especially in a young patient with unremarkable
medical history, and because of the similarity of symptoms with migraine.
Often there is no obvious cause of a cerebral artery dissection, although
subtle abnormalities of connective tissue may be present. Anticoagulation
is generally used for therapy, but clinical trials are lacking. Carotid artery
dissection should be considered as a cause of stroke in young healthy adults.
Wityk RJ. Stroke in a Healthy 46-Year-Old Man. JAMA. 2001;285(21):2757-2762. doi:10.1001/jama.285.21.2757