[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
June 20, 2001

Food Fortification to Prevent Neural Tube DefectsIs It Working?

Author Affiliations

Author Affiliation: Pediatric Epidemiology Section, Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md.

JAMA. 2001;285(23):3022-3023. doi:10.1001/jama.285.23.3022

Whether your dinner plans include tacos, spaghetti carbonara, crispy fried rice, or just a bacon-lettuce-tomato on toast, you can bet that you will be having folic acid tonight. Since January 1, 1998, the US Food and Drug Administration (FDA) has required that all enriched cereal grains must be fortified with 140 µg of folic acid per 100 g of grain.1 This regulation was introduced because folic acid, taken prior to conception, can prevent many neural tube defects (NTDs) and because an alarming number of women of childbearing age were not following the US Public Health Service recommendation to take 400 µg/d of folic acid routinely.

First Page Preview View Large
First page PDF preview
First page PDF preview