Author Affiliation: Cerebrovascular Section, NeuroImaging Laboratory and Interventional Neuroradiology Service, Neuroradiology Section, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo.
Contempo Updates Section Editor: Alice T.
D. Hughes, MD, Fishbein Fellow.
Physiological imaging tools have provided a window for the study of
central nervous system physiology and pathophysiology in living humans, particularly
in the areas of cerebral ischemia and cognitive neuroscience. The first studies
in living humans were performed nearly 50 years ago and involved measurements
of whole brain blood flow using radiotracers.1
It is now possible to measure many dynamic physiological processes within
small regions of the brain. These processes include blood flow, oxygen and
glucose metabolism, electrical activity, nuclear magnetic spectra, and neurotransmitter
Derdeyn CP. Physiological Neuroimaging: Emerging Clinical Applications. JAMA. 2001;285(24):3065–3068. doi:10.1001/jama.285.24.3065