Cambridge, Mass—Recent studies by researchers
at Massachusetts Institute of Technology (MIT) are providing a clearer view
of how alterations in lens proteins make cataract formation more likely to
occur. Elucidation of these molecular mechanisms should help identify methods
to inhibit or prevent cataract development and may also provide useful clues
to the pathogenesis of other conditions, such as Alzheimer disease.
New strategies for treating or preventing cataract would be welcome.
According to the World Health Organization, cataract is the leading cause
of vision impairment worldwide and is responsible for half of the 45 million
cases of blindness that occur across the globe. Currently the only treatment
for this condition is extraction of the cataract.
Friedrich MJ. Insight Into Opacity: Clues to Cataract Formation. JAMA. 2001;286(14):1705. doi:10.1001/jama.286.14.1705