JAMA 100 Years Ago Section Editor: Jennifer
Reiling, Assistant Editor.
The interest in the relation of diabetes to lesions in the pancreas
has been much increased by the recent demonstration of more or less definite
changes in the so-called islands of Langerhans in many cases of this disease.
The final explanation of diabetes must be sought by chemical methods, and
the most recent work of Herter and others on adrenalin diabetes, to which
reference has been made in these columns from time to time, is extremely suggestive
and important. In the meantime the finer morphologic changes that there is
good reason to believe may constitute the anatomic substratum of spontaneous
pancreatic diabetes will appeal to many as an interesting field of research.
No doubt many facts of value will accumulate in time from investigations in
THE PANCREAS IN DIABETES.. JAMA. 2002;287(19):2470. doi:10.1001/jama.287.19.2470