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Contempo Updates
June 26, 2002

Contemporary Concepts of the Pathogenesis and Management of Preeclampsia

Author Affiliations

Author Affiliations: Magee-Womens Research Institute and Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pa.

 

Contempo Updates Section Editor: Janet M. Torpy, MD, Fishbein Fellow.

JAMA. 2002;287(24):3183-3186. doi:10.1001/jama.287.24.3183

Preeclampsia is a pregnancy-specific form of hypertension that presents a major health problem worldwide. Preeclampsia complicates 5% to 8% of all pregnancies and increases both maternal and neonatal morbidity and mortality.1,2 The mainstay of therapy for preeclampsia remains clinical recognition through prenatal care and termination of the disease process with delivery. Maternal mortality has been reduced in the United States, but in countries where prenatal care is not adequate, preeclampsia/eclampsia accounts for 40% to 80% of maternal deaths, an estimated 50 000 per year. Many of these deaths may be preventable with prenatal care and evidence-based prophylactic seizure therapy.

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