Author Affiliations: Department of Health, Ministry of Public Health, Nonthaburi, Thailand (Drs Kanshana and Amornwichet); The Thailand Ministry of Public Health–US Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand (Drs Teeraratkul and Tappero, and Mss Naiwatanakul, Chantharojwong, and Culnane); Global AIDS Program, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Ga (Drs Simonds and Tappero and Ms Culnane).
Section Editor: Annette Flanagin, RN, MA,
Managing Senior Editor.
Context Each year in Thailand, about 10 000 children are born at risk for
mother-to-child human immunodeficiency virus (HIV) transmission. In 2000,
Thailand implemented a national program to prevent mother-to-child HIV transmission.
Objective To describe the results of implementation of the program.
Design Monthly collection of summary data from hospitals.
Setting Public health hospitals (n = 822) in all 12 regions of Thailand, representing
75 provinces, excluding Bangkok.
Participants Women giving birth from October 2000 through September 2001, including
HIV-seropositive women and their neonates.
Main Outcome Measures Percentages of women giving birth who were tested for HIV, HIV-seropositive
women giving birth who received antenatal prophylactic antiretroviral drugs,
and HIV-exposed neonates who received prophylactic antiretroviral drugs and
Results Among 573 655 women (range, 27 344-77 806 by region)
giving birth, 554 912 (96.7%) received antenatal care (range, 91.9%-98.8%
by region). Of 554 912 women giving birth who had antenatal care, 517 488
(93.3%) were tested for HIV (range, 87.7%-99.4% by region) before giving birth;
of 18 743 women giving birth who did not have antenatal care, 13 314
(71.0%) were tested for HIV (range, 21.7%-92.9% by region). Of 6646 HIV-seropositive
women giving birth, 4659 (70.1%) received prophylactic antiretroviral drugs
before delivery (range, 55.3%-81.2% by region). Of 6475 neonates of HIV-seropositive
women, 5741 (88.7%) received prophylactic antiretroviral drugs (range, 67.4%-96.9%
by region) and 5386 (83.2%) received infant formula (range, 65.3%-100% by
Conclusions Major program components of Thailand's national program for preventing
mother-to-child HIV transmission were implemented. Thailand's experience may
encourage other developing countries to implement or expand similar national
Amornwichet P, Teeraratkul A, Simonds RJ, Naiwatanakul T, Chantharojwong N, Culnane M, Tappero JW, Kanshana S. Preventing Mother-to-Child HIV TransmissionThe First Year of Thailand's National Program. JAMA. 2002;288(2):245-248. doi:10.1001/jama.288.2.245