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November 13, 2002

Thrombolytic Therapy vs Angioplasty in Acute Myocardial Infarction

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2002;288(18):2263-2264. doi:10.1001/jama.288.18.2263

To the Editor: Dr Aversano and colleagues1 found that primary percutaneous coronary intervention (PCI) resulted in better outcomes than thrombolytic therapy in patients with acute myocardial infarction (MI). We are concerned that the results may be confounded by medications likely to modify the outcome. In particular, it would be helpful to know the proportions of patients who actually received glycoprotein IIb/IIIa inhibitors, other platelet function inhibitors, low-molecular-weight heparin, β-blockers, angiotensin-converting enzyme inhibitors, and cholesterol-lowering drugs.

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