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Contempo Updates
Clinician's Corner
December 25, 2002

Current Controversies in VaccinationVaccine Safety

Author Affiliations

Author Affiliations: Department of Pediatrics, Stanford University School of Medicine, Stanford, and Lucile Salter Packard Children's Hospital at Stanford, Palo Alto, Calif.


Contempo Updates Section Editor: Janet M. Torpy, MD, Contributing Editor.

JAMA. 2002;288(24):3155-3158. doi:10.1001/jama.288.24.3155

Vaccination is ranked as one of the 10 greatest public health achievements of the last century and is the number one contribution to decreased global morbidity and mortality.13 Pediatric vaccinations have had the most profound impact of any intervention on increasing global child survival, accounting for 3 million pediatric lives saved annually.3 However, even in the 21st century, vaccine-preventable infectious diseases remain important causes of morbidity and mortality in many areas of the world. Globally, tetanus, measles, and pertussis are the main vaccine-preventable causes of death in children; septicemia and influenza-related pneumonia are among the top 10 causes of death in adults and children worldwide, including the United States.4,5

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