Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Ms Graat and colleagues1 found that multivitamin supplements did not prevent
acute respiratory tract infections in healthy elderly persons. The authors
used a multivitamin and trace-element preparation that contained recommended
daily allowances (RDAs) of vitamins but only 25% to 50% of the RDAs for minerals.
The RDAs, however, are intended to prevent nutritional deficiency, and may
be too low to produce further benefits.2,3 Other
studies, using nutrients in amounts based on physiological dose-response curves
and immune responses, have found beneficial effects.4,5
Chandra RK. Vitamin Supplementation in Elderly Persons. JAMA. 2003;289(2):173. doi:10.1001/jama.289.2.173-a