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January 8, 2003

Pulse Pressure and Risk of Cardiovascular DiseasePulse Pressure and Risk of Cardiovascular Disease

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;289(2):174-175. doi:10.1001/jama.289.2.174-a

To the Editor: Dr Domanski and colleagues1 concluded that pulse pressure alone may not be as strong a predictor of cardiovascular disease-related mortality as SBP and DBP together.

The subjects in this study only included men aged 35 to 57 years, an age that may be too young to associate pulse pressure with cardiovascular events. Several previous studies have found that pulse pressure is a predictor of coronary events in patients aged 60 years or older.24 Thus, the study of Domanski et al may not be a conclusive indicator of the risk of elevated pulse pressure in all age groups.

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