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Health Agencies Update
January 15, 2003

Hospital Quality Program

JAMA. 2003;289(3):290. doi:10.1001/jama.289.3.290-a

The National Institutes of Health has added steroidal estrogens and oral contraceptives to its list of known human carcinogens. Together with 15 other new listings, including ultraviolet radiation and wood dust, 228 substances are now "known" or "reasonably anticipated" to pose a cancer risk, according to the 10th Report on Carcinogens prepared by the National Toxicology Program of the National Institute of Environmental Health Sciences.

In listing estrogens, the report cites recent large studies that show an association between estrogen replacement therapy and a consistent increase in the risk of endometrial and breast cancers.

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