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Clinical Crossroads
Clinician's Corner
January 22/29, 2003

A 59-Year-Old Woman With Gastroesophageal Reflux Disease and Barrett Esophagus

Author Affiliations

Author Affiliations: Dr Spechler is Chief, Division of Gastroenterology, Dallas Veterans Affairs Medical Center, and Professor of Medicine and Berta M. and Cecil O. Patterson Chair in Gastroenterology, The University of Texas Southwestern Medical Center at Dallas.


Clinical Crossroads Section Editor: Margaret A. Winker, MD, Deputy Editor.

JAMA. 2003;289(4):466-475. doi:10.1001/jama.289.4.466

DR BURNS: Mrs J is a 59-year-old woman with a long history of gastroesophageal reflux disease (GERD) and documented Barrett esophagus. She lives near Boston with her husband and has 2 grown children. She sees her primary care physician, Dr W, and she has managed care insurance.

Mrs J initially developed symptoms of heartburn in the early 1990s and was prescribed ranitidine, 150 mg/d, which was later increased to twice daily without improvement. In 1993, Mrs J underwent an upper GI series, the results of which were normal; in 1994, test results for Helicobacter pylori were negative.

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