Author Affiliations: Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Contrast nephropathy is one of the well-recognized risks of coronary
angiography. Although the disease occurs infrequently with normal renal function,
its frequency increases with decreasing renal function, ranging from 5% in
patients with mild renal insufficiency1 to
50% in those with severe renal dysfunction and diabetes.2 Given
that contrast nephropathy is associated with increased morbidity, mortality,
and length of hospitalization, and possibly with long-term renal impairment,3 there is great interest in its prevention.
Curhan GC. Prevention of Contrast Nephropathy. JAMA. 2003;289(5):606-608. doi:10.1001/jama.289.5.606