To the Editor: Dr Solomon and colleagues1 reported that 6 weeks of treatment with Ginkgo biloba failed to improve performance on standardized neuropsychological
tests of learning, memory, attention, and verbal ability in healthy elderly
adults without cognitive impairment. The authors argue that clinical findings
to date have not supported claims that ginkgo improves cognitive efficiency.
Their study, however, is not directly comparable with prior studies, which
have varied significantly in terms of trial durations, predictor and outcome
measures used, and the type of cohort tested. Moreover, the authors do not
mention several methodologically comparable studies,2,3 including
our 1-month trial,4 which have reported
selective improvements in neuropsychological status in young adults and healthy
older subjects treated with ginkgo.
Nathan PJ, Harrison BJ, Bartholomeusz C. Ginkgo and Memory. JAMA. 2003;289(5):546. doi:10.1001/jama.289.5.546-a