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February 5, 2003

Ginkgo and MemoryGinkgo and Memory

JAMA. 2003;289(5):546. doi:10.1001/jama.289.5.546-a

To the Editor: Dr Solomon and colleagues1 studied the effect of ginkgo in enhancing cognitive abilities among individuals with normal baseline function. It is unclear, however, whether these negative results apply to a population with impaired cognitive function.

By contrast, Le Bars et al2 reported significant improvement among patients with either multi-infarct dementia or Alzheimer disease. For such individuals, clinicians in Europe generally use the higher dose of 240 mg/d for at least 3 months. The results of Solomon et al do not rule out a beneficial effect of this higher dosage in the subjects they tested.

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