A study of brain tissue from patients who died after bone marrow transplants
has provided convincing evidence that blood stem cells can migrate to the
brain and blossom into clumps of active gray and white matter, report researchers
from the National Institute of Neurological Disorders and Stroke (NINDS) and
the Johns Hopkins Medical Institutions.
Previous experiments had shown that 1% to 2% of all neurons in mice
that had received bone marrow transplants were derived from blood stem cells.
"I thought this was all well and good for mousekind, but what about people?"
said Éva Mezey, MD, PhD, a neuroanatomist at the NINDS.
Vastag B. From Blood Cells to Neurons. JAMA. 2003;289(7):833. doi:10.1001/jama.289.7.833-a