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Medical News and Perspectives
February 26, 2003

Panel Endorses Limited Role for CRP Tests

JAMA. 2003;289(8):973-974. doi:10.1001/jama.289.8.973

Patients at intermediate risk of developing cardiovascular disease (CVD) present their physicians with a vexing question: Should these patients—those who have a 10% to 20% chance of developing coronary heart disease over the next 10 years—try to avoid CVD through lifestyle modifications, or are more aggressive medical therapies warranted?

That question prompts another one: How should physicians determine appropriate interventions for such patients? Should they rely on the Framingham Heart Study Prediction Score, or couple that information with further evaluations, such as imaging and exercise testing?

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