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Letters
March 12, 2003

Blood Transfusions and Mortality Among Critically Ill Patients—Reply

Author Affiliations
 

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;289(10):1243-1244. doi:10.1001/jama.289.10.1243-a

In Reply: We agree with Dr Renshaw that future advances in understanding of pedophilia will likely rest in the hands of science and medicine. Recent technological developments that allow for a detailed study and exploration of the mind/brain relationship could prove to be the crucial complement to the behavioral, pharmacological, and psychotherapeutic interventions currently in practice. A study conducted on a group of patients with sexual disorders including pedophilia has documented that endogenously produced opiates are released in specific brain areas during sexual arousal.1 It is unknown, however, whether the pathological release of such opiates may explain the addictive quality sometimes associated with sexual drive in some pedophilic patients. Similarly, it is possible that the pattern of opiate release in various brain areas differ in either an aroused, or an unaroused, sexual state between persons who either are, or are not, sexually disordered.

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