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March 12, 2003

Hepatitis C Virus and Atherosclerosis in Patients With Type 2 Diabetes

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;289(10):1245-1246. doi:10.1001/jama.289.10.1245-a

To the Editor: Epidemiologic studies have suggested possible atherogenic roles for such pathogens as Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus.1 However, few data are available on the relation between hepatitis C virus (HCV) infection and atherosclerosis.2 With the availability of more reliable assays, HCV infection is emerging as an extremely common and insidiously progressive disease. The prevalence of antibodies to HCV (anti-HCV) in patients with diabetes was reported to be higher than in healthy blood donors.3 We therefore investigated whether HCV might have a pathogenic effect in atherosclerosis among patients with type 2 diabetes.

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