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Letters
March 19, 2003

Diuretics in Critically Ill Patients With Acute Renal FailureDiuretics in Critically Ill Patients With Acute Renal Failure

Author Affiliations
 

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;289(11):1379-1381. doi:10.1001/jama.289.11.1379-a

To the Editor: Dr Mehta and colleagues1 concluded that the use of diuretics in critically ill patients with ARF is associated with a poor outcome. Even though the authors indicate that observational data prohibit causal inference, they argue that in the absence of compelling contradictory data from clinical trials, the widespread use of diuretics in critically ill patients with ARF should be discouraged. This conclusion, however, may be flawed since the methods used by the authors do not regard the epidemiological theory of causality.

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