Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Dr Steinhubl and colleagues1 found that following PCI with clopidogrel therapy,
in addition to traditional aspirin therapy, significantly reduced the likelihood
of adverse events at 1 year. They also found that a loading dose of clopidogrel
at least 3 hours prior to the procedure did not reduce events at 28 days,
but that a loading dose of clopidogrel at least 6 hours prior to PCI may offer
Bridges JFP. Clopidogrel and Percutaneous Coronary Interventions. JAMA. 2003;289(15):1925-1927. doi:10.1001/jama.289.15.1925-a