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Books, Journals, New Media
May 7, 2003

Assisted ReproductionAssisted Reproduction

Author Affiliations

Books, Journals, New Media Section Editor: Harriet S. Meyer, MD, Contributing Editor, JAMA; David H. Morse, MS, University of Southern California, Norris Medical Library, Journal Review Editor.

JAMA. 2003;289(17):2288. doi:10.1001/jama.289.17.2288-a

IVF Childen describes the first generation of children conceived through in vitro fertilization (IVF) in six chapters. The author intends it "for nonclinical scientists, for parents of children conceived with the help of ART [assisted reproductive technologies], and for the purposes of refuting any myths created about these children (positive or negative)."

The first chapter is an excellent short overview of the development of IVF, including interesting historical notes and concise descriptions of IVF, embryo freezing, and intracytoplasmic sperm injection (ICSI). Outcomes, including congenital anomalies, perinatal health and morbidity, growth and neural developmental well-being, and family relationships, are considered for each therapy. The author carefully outlines pitfalls in comparisons, such as the observation that women undergoing ART are usually older than women conceiving naturally and that babies born after ART may be monitored more carefully, thus artificially increasing the relative frequency of anomalies reported.

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