JAMA 100 Years Ago Section Editor: Jennifer Reiling, Assistant Editor.
During recent years workers in bacteriology have been largely occupied
with the study of the soluble products of bacteria and with their action on
the animal body. In view of the brilliant results which followed the discovery
and investigation of the soluble toxins of the tetanus and diphtheria bacilli,
it was natural to seek similar poisons in connection with the other pathogenic
bacteria with the hope of also obtaining specific anti-toxic agents to combat
them. However, it soon became apparent that many bacteria did not exert their
injurious effects through the agency of soluble toxins, and efforts to obtain
curative sera by injections of fluid cultures have met with complete failure
in the case of most pathogenic bacteria.
WAITING-ROOM LITERATURE.. JAMA. 2003;289(17):2292. doi:10.1001/jama.289.17.2292-a