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Medical News and Perspectives
May 7, 2003

Researchers Probe Aortic Stenosis

JAMA. 2003;289(17):2197-2198. doi:10.1001/jama.289.17.2197

Chicago—An age-old problem may not be an old-age phenomenon as conventional wisdom has believed.

The cardiology community has long assumed that aortic stenosis is a wear-and-tear, degenerative process caused, in part, by a heart beating for many decades. But research over the past few years suggests a different, more active, cause—lipoprotein deposits and inflammation of the aortic valve, with resulting calcification and ossification.

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