Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
In Reply: We agree that meta-analyses must
always be interpreted with caution, as they are challenged by the "mixed salad
principle," that is, by the heterogeneity of evidence reported.1 However,
a number of methods exist that allow researchers to integrate heterogeneous
evidence to examine the consistency and applicability of findings across studies
of various types.2 Ideally, systematic reviews
would include all relevant studies, regardless of language of publication.
Limited time and resources may preclude such an approach.
Bekelman JE, Gross CP, Li Y. Economic Issues in the Residency Match. JAMA. 2003;289(19):2502-2503. doi:10.1001/jama.289.19.2502-a