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June 4, 2003

Acetylcysteine and Renal Function Following Coronary Angiographic ProceduresAcetylcysteine and Renal Function Following Coronary Angiographic Procedures

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;289(21):2794-2796. doi:10.1001/jama.289.21.2794-a

To the Editor: I have several concerns about the study of Dr Kay and colleagues.1 First, the authors reported a length of hospitalization of 3.9 days in control group and 3.4 days in the acetylcysteine group. In a previous study that analyzed contrast nephropathy after elective coronary angiography with or without intervention, the length of hospitalization in the control group was only 1.3 days.2 It would be of interest to know why the length of stay was so much longer in the study by Kay et al, especially as there were only 2 complications reported and none of the participants required dialysis. It also would be of interest to know the management of patients with acute contrast-induced reduction in renal function.

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