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The World in Medicine
June 11, 2003

Egging on Stem Cells

JAMA. 2003;289(22):2929. doi:10.1001/jama.289.22.2929-a

Researchers from the United States and France have succeeded in growing mouse egg cells from both male and female embryonic stem cells in laboratory cultures. The report was published online on May 2 on the Web site of Science (http://www.sciencemag.org) and in print in the journal's May 23 issue.

Previous efforts to coax cultured embryonic stem cells to develop into egg or sperm cells had been unsuccessful; the feat is the first demonstration that mammalian embryonic stem cells remain totipotent, or capable of developing into every cell type, even outside the body.

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