Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Landmark clinical trials can
influence prescribing behavior.1- 3 We
examined patterns of prescriptions for estrogen replacement therapy (ERT)
before and after publication of the Women's Health Initiative (WHI) study4 on July 17, 2002. We also examined trends around
the publication of the Heart and Estrogen/progestin Replacement Study (HERS)5 in 1998.
Austin PC, Mamdani MM, Tu K, Jaakkimainen L. Prescriptions for Estrogen Replacement Therapy in Ontario Before and After Publication of the Women's Health Initiative Study. JAMA. 2003;289(24):3241-3242. doi:10.1001/jama.289.24.3241