Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: In their meta-analysis, Dr Bradley
and colleagues1 concluded that cardiac resynchronization
reduces mortality from progressive heart failure in patients with symptomatic
left ventricular dysfunction. We have several concerns, however, about their
representation and interpretation of current data.
First, the review is incomplete because it failed to include at least
1 published randomized trial,2 in which
no deaths occurred; excluded another3 without
explanation; and only partially reported data in the public domain for a third.4
Cleland JGF, Freemantle N. Cardiac Resynchronization for Progressive Heart Failure—Reply. JAMA. 2003;290(1):36-37. doi:10.1001/jama.290.1.36-a