Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
In Reply: We appreciate the efforts of Dr Folsom
and colleagues to replicate our findings on nut consumption and risk of type
2 diabetes, and we agree that further research is needed given the limited
data. However, we are concerned that overadjustment may have contributed to
major change in their multivariate analysis, because fiber, magnesium, and
monounsaturated and polyunsaturated fat are all major components of nuts and
peanut butter. We also point out that such adjustment had negligible effects
on the results in our analysis. We share their concern that nonspecificity
of self-reported diabetes might have contributed to attenuation of the results
in the Iowa Women's Health Study.
Jiang R, Manson JE, Stampfer MJ, Liu S, Willett WC, Hu FB. Nut Consumption and Risk of Type 2 Diabetes. JAMA. 2003;290(1):38-39. doi:10.1001/jama.290.1.38