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July 16, 2003

Early Exposure to Marijuana and Risk of Later Drug UseEarly Exposure to Marijuana and Risk of Later Drug Use

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;290(3):329. doi:10.1001/jama.290.3.329-a

To the Editor: Dr Lynskey and colleagues1 used a matched cohort design to study the association between cannabis use by the age of 17 years with drug use later in life. Twins who had used cannabis by the age of 17 years were matched with their sibling who had not used cannabis by that age. This design eliminates possible confounding by any shared genetic and environmental factors. The authors estimated odds ratios (ORs) using conditional logistic regression.

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