Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: In their Research Letter, Dr
Pacifici and colleagues1 found that long-term
users of cannabis had lower natural killer cell counts, lymphocyte proliferation,
and levels of interleukin 2 (IL-2), as well as increased levels of IL-10 and
transforming growth factor-β-1. The authors concluded that this pattern
of results may reflect immunosuppressive properties of cannabis.
Killestein J, Uitdehaag BMJ, Polman CH. Cannabinoids and Immune Function. JAMA. 2003;290(6):754. doi:10.1001/jama.290.6.754-a