Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Dr Thompson and colleagues1 reported that 7% of cases of statin-induced rhabdomyolysis
in the US Food and Drug Administration (FDA) Qscan database from November
1997 through March 2000 were associated with a coprescription for macrolide
antibiotics. Such coprescriptions, however, only accounted for 3% of such
incidents between January 1990 and March 2002. It is unclear whether this
represents a class effect or is due only to specific macrolide antibiotics.
Luh JY, Karnath BM. Issues in Statin-Associated Myopathy—Reply. JAMA. 2003;290(7):888. doi:10.1001/jama.290.7.888-a