Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: We wish to raise some methodological
concerns about the article by Dr Al-Khatib and colleagues.1
Although the authors described a MEDLINE search, they did not provide
a critical summary of published reports of drugs affecting the QT interval.
Similarly, they did not include information from pharmacovigilance or postmarketing
databases. Rather, their main table of results is based on an opinion survey
whose methods and results were not presented.
Gillespie JA, Clary CM. Medications That Prolong the QT IntervalMedications That Prolong the QT Interval. JAMA. 2003;290(8):1025. doi:10.1001/jama.290.8.1025-a