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August 27, 2003

Medications That Prolong the QT IntervalMedications That Prolong the QT Interval

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2003;290(8):1025. doi:10.1001/jama.290.8.1025-a

To the Editor: We wish to raise some methodological concerns about the article by Dr Al-Khatib and colleagues.1

Although the authors described a MEDLINE search, they did not provide a critical summary of published reports of drugs affecting the QT interval. Similarly, they did not include information from pharmacovigilance or postmarketing databases. Rather, their main table of results is based on an opinion survey whose methods and results were not presented.

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