Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Dr Hébert and colleagues1 found that a national universal leukoreduction
program for red blood cell (RBC) transfusion reduced the rates of mortality
and morbidity after RBC transfusions in high-risk patients. Although the authors
state that RBCs transfused in the period before the introduction of the policy
were stored in an additive solution, they do not indicate whether any of these
units underwent depletion of the buffy coat. It also would be important to
know about clinical use of microaggregate filters at the bedside.
Wallis JP. Leukoreduction vs Buffy-Coat Depletion and the Safety of Blood Transfusion. JAMA. 2003;290(12):1580. doi:10.1001/jama.290.12.1580-a