[Skip to Content]
[Skip to Content Landing]
Citations 0
The World in Medicine
October 15, 2003

PAHO Influenza Plan

JAMA. 2003;290(15):1984. doi:10.1001/jama.290.15.1984-a

Scientists in Iceland report they have discovered a gene associated with an increased risk for ischemic stroke. The new findings were published online on September 21 by Nature Genetics (http://www.nature.com/ng/).

The newly identified stroke-susceptibility gene, PDE4D, encodes an enzyme called phosphodiesterase 4D, which previously had not been implicated in stroke. Phosphodiesterase breaks down cyclic adenosine monophosphate, a molecule with many biological roles—one of which affects proliferation and migration of vascular cells, and thus may be involved in promoting atherosclerosis.

First Page Preview View Large
First page PDF preview
First page PDF preview