Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.
To the Editor: Mildly elevated levels of aminotransferase
have been reported in 23% to 50% of patients with severe acute respiratory
syndrome (SARS). The clinical and pathological significance of this finding,
however, remains unknown.1- 3 We
investigated whether liver dysfunction might reflect disease activity and
have a temporal relationship with other clinical parameters in patients with
Wong W, Ho JC, Hung IF, Ng W, Lam Y, Tam W, Wong BCY, Wong PC, Lai CL, Lam W, Lam S, Tsang KW, Ooi GC, Ho PL, Mok T, Chan J. Temporal Patterns of Hepatic Dysfunction and Disease Severity in Patients With SARS. JAMA. 2003;290(20):2663–2665. doi:10.1001/jama.290.20.2663