Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
In Reply: We agree with Dr Burke that the optimal
proof of the role of physical activity in the etiology of breast cancer would
come from a randomized clinical trial. Short of that, randomized controlled
trials of the effect of physical activity on biomarkers of breast cancer would
be useful.1 Unfortunately, few such studies
McTiernan A, White E, Kooperberg C. Exercise and Risk of Breast Cancer—ReplyExercise and Risk of Breast Cancer—Reply. JAMA. 2003;290(24):3193. doi:10.1001/jama.290.24.3193-a