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January 7, 2004

Changes in Prescribing Patterns Following Publication of the ALLHAT Trial

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(1):44-45. doi:10.1001/jama.291.1.44-b

To the Editor: Antihypertensive agents are among the most commonly prescribed medications for elderly persons in North America.1 The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT), published on December 18, 2002, concluded that thiazide-type diuretics should be the first-step antihypertensive therapy, compared with either calcium channel blockers (CCBs) or angiotensin-converting enzyme (ACE) inhibitors.2 We examined trends in incident use of antihypertensive agents following publication of the ALLHAT trial.

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