Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
In Reply: Dr Rockhill claims that the prevalence
of conventional risk factors is similar between patients with and without
CHD, as the number of individuals with at least 1 conventional risk factor
did not differ dramatically between coronary heart disease and noncoronary
heart disease cohorts in the study by Greenland et al.1 However,
this is not the same as showing that the prevalence of conventional risk factors
are similar in the 2 groups. In fact, data from Table 4 of the article by
Greenland et al clearly support our statement showing that the prevalence
of cigarette smoking, diabetes, hyperlipidemia, and hypertension were significantly
higher in individuals with CHD compared with individuals without CHD in nearly
all subgroups. Thus, we believe that it remains accurate to state that the
prevalence of conventional risk factors in patients with CHD is substantially
greater than the prevalence in the general population.
Khot UN, Khot MB, Topol EJ. Traditional Risk Factors for Coronary Heart Disease—Reply. JAMA. 2004;291(3):299. doi:10.1001/jama.291.3.300-a