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January 21, 2004

Antibiotics and Coronary Heart Disease

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(3):302. doi:10.1001/jama.291.3.302-a

To The Editor: Dr O'Connor and colleagues1 reported that a 3-month course of azithromycin did not significantly reduce the clinical sequelae of coronary heart disease (CHD) among stable patients with previous myocardial infarction and evidence of Chlamydia pneumoniae exposure. Exposure to this pathogen is, in fact, highly prevalent in the population (more than 80% of people older than 65 years may have the antibody).2

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