Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
In Reply: In the study of Dr Taylor and colleagues,1 women with regular menstrual cycles and basal FSH
levels of 7 mIU/mL or greater had higher cholesterol levels than a similar
group with lower FSH levels. Estradiol levels were greater in the group with
high FSH levels. Thus, Taylor infers that deficiency for ovarian factor(s)
other than estradiol, signaled by elevation of FSH levels, impairs cholesterol
metabolism. Although we find this an interesting and novel hypothesis, our
results are actually not similar to those of Taylor et al, and do not appear
to support this view.
Bondy CA, Bakalov VK. Genetic vs Hormonal Factors in Lipid Metabolism in Women—Reply. JAMA. 2004;291(4):424-425. doi:10.1001/jama.291.4.425-a