[Skip to Content]
[Skip to Content Landing]
Citations 0
January 28, 2004

Genetic vs Hormonal Factors in Lipid Metabolism in Women—Reply

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(4):424-425. doi:10.1001/jama.291.4.425-a

In Reply: In the study of Dr Taylor and colleagues,1 women with regular menstrual cycles and basal FSH levels of 7 mIU/mL or greater had higher cholesterol levels than a similar group with lower FSH levels. Estradiol levels were greater in the group with high FSH levels. Thus, Taylor infers that deficiency for ovarian factor(s) other than estradiol, signaled by elevation of FSH levels, impairs cholesterol metabolism. Although we find this an interesting and novel hypothesis, our results are actually not similar to those of Taylor et al, and do not appear to support this view.

First Page Preview View Large
First page PDF preview
First page PDF preview