Experiencing a mild stroke may alter the brain in such a way that serves
to protect it from future attacks, according to research funded by the National
Institute of Neurological Disorders and Stroke (Lancet.
The researchers found that "preconditioned" mice—animals that
had transient ischemic attacks caused when the cerebral artery was blocked
for 15 minutes—experienced a 70% decrease in brain damage during a second,
larger attack compared with control mice. The authors suggest that a preconditioned
mouse experiences altered expression of certain genes in anticipation of a
future, larger stroke.
Hampton T. Stifling Subsequent Strokes. JAMA. 2004;291(8):933. doi:10.1001/jama.291.8.933-a