Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
To the Editor: Dr Rosenheck and colleagues1 reported that olanzapine did not demonstrate advantages
compared with haloperidol (in combination with prophylactic benztropine) in
compliance, symptoms, extrapyramidal symptoms, or overall quality of life
among patients with schizophrenia or schizoaffective disorder The authors
also found that olanzapine was associated with better cognitive function and
motor function (including less tardive dyskinesia) than haloperidol, but also
with greater weight gain.
Glazer WM. Olanzapine vs Haloperidol for Treatment of Schizophrenia. JAMA. 2004;291(9):1064. doi:10.1001/jama.291.9.1064-b