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March 3, 2004

Olanzapine vs Haloperidol for Treatment of Schizophrenia

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(9):1064. doi:10.1001/jama.291.9.1065-b

To the Editor: Dr Rosenheck and colleagues1 reported improvement of approximately 15 points in symptom scores in the group treated with olanzapine vs an approximately 10-point difference in those treated with haloperidol. The authors did not perform statistical comparisons within each group, however; thus, it is difficult to know if these differences are statistically significant or clinically meaningful.

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