Letters Section Editor: Stephen J. Lurie,
MD, PhD, Senior Editor.
In Reply: In response to Dr Kim and colleagues,
because of the 3 species and multiple preparations of echinacea that are commonly
used, it is difficult to select a single, optimal product for study. This
selection is further complicated by the lack of identification of a single
constituent, or group of constituents, that is responsible for the putative
clinical effects of echinacea. Thus, rather than choosing a formulation on
the basis of a group of chemical constituents, we used an extract of the above-ground E purpurea plant that has been reported to be effective
in treating URIs in adults.1,2 Our
study medication was standardized by comparison to the fresh-squeezed juice
of the plant.
Taylor JA, Weber W, Standish L, McGann M, Calabrese C. Echinacea for Treating Colds in Children—Reply. JAMA. 2004;291(11):1323-1324. doi:10.1001/jama.291.11.1324