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Student JAMA
April 7, 2004

The Clinical Relevance of Genomic Variation

JAMA. 2004;291(13):1641. doi:10.1001/jama.291.13.1641

Driven by the recent sequencing of the human genome, the field of genetics has evolved to include the study of interindividual genomic variation. This emerging discipline focuses on the 0.1% of our genome that makes each individual genetically unique.1 Understanding genomic variation may improve the prediction of disease susceptibility, prognosis, and response to drug therapy, although a number of challenges will need to be addressed before this approach can be integrated into standard clinical practice.

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