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April 21, 2004

Use of Coronary Calcification Scores to Predict Coronary Heart Disease

Author Affiliations

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(15):1831. doi:10.1001/jama.291.15.1831-a

To the Editor: Dr Greenland and colleagues1 reported that both the Framingham Risk Score (FRS) and the coronary artery calcium score (CACS) were predictive of coronary artery disease. The authors also reported that across categories of FRS, CACS was predictive of risk among patients with an FRS higher than 10%, but not with an FRS less than 10%. Furthermore, the CACS was less predictive than the FRS (hazard ratio, 3.9 vs 14.3), and only added slightly to the area under the receiver operating characteristic (ROC) curve using FRS alone.

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