[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.166.74.94. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Letters
April 21, 2004

Use of Coronary Calcification Scores to Predict Coronary Heart Disease

Author Affiliations
 

Letters Section Editor: Stephen J. Lurie, MD, PhD, Senior Editor.

JAMA. 2004;291(15):1831. doi:10.1001/jama.291.15.1832-a

To the Editor: Dr Greenland and colleagues1 stated that "absence of CACS did not preclude the risk of a CHD [coronary heart disease] event as has been reported in some other studies." However, in explaining why individuals without detectable CAC might experience coronary events, the authors did not consider that their scanning methodology used a 6-mm scan thickness, twice the scan thickness used in other prognostic studies. For instance, Callister et al2 evaluated patients with both 3-mm and 6-mm scans and concluded that "[a] 6-mm slicing protocol is significantly less sensitive than a 3-mm protocol for the detection and quantification of CAC. Since one-third of coronary events occur in patients with low CACS, a 6-mm protocol might be unreliable for risk assessment because of substantial loss of information."

First Page Preview View Large
First page PDF preview
First page PDF preview
×